Lowell, Massachusetts, a city rich in history and culture, has embraced the evolving cannabis landscape with a selection of top-tier dispensaries. From locally cultivated strains to a wide array of edibles and concentrates, these dispensaries prioritize quality, education, and community engagement.
In this guide, we’ll introduce you to some of the standout dispensaries in Lowell, highlighting what makes each unique and worth a visit.
Mayflower
Right in the heart of the Merrimack Valley, Mayflower’s Lowell dispensary is all about delivering a cannabis experience that’s welcoming, transparent, and community-focused. Located on Chelmsford Street, this shop offers a carefully curated menu featuring premium flower, edibles, concentrates, and more, including products from trusted local Massachusetts producers.
At Mayflower, we’re here to create impact. Through programs like our Positive Impact Plan, Fellowship Program, and the Mayflower Artist Spotlight Series (M.A.S.S.), we’re committed to supporting equity, opportunity, and creativity in the communities we serve.

Smyth Cannabis Co.
At Smyth Cannabis Co., attention to detail is the foundation of everything they do. Their flagship dispensary on Rogers Street in Lowell delivers a premium adult-use experience from start to finish, with a sleek retail space, knowledgeable staff, and a product lineup that reflects true craftsmanship.
Behind the scenes, Smyth’s 15,000-square-foot cultivation facility is where the magic happens. Every batch of flower is small-batch grown, hand-trimmed, and properly cured to ensure consistent quality and a genuine craft feel in every jar.
Cannabist
Cannabist brings a thoughtful, elevated vibe to cannabis retail that’s rooted in premium products, strong values, and an approachable, curated experience. From the moment you walk in, it’s clear they’ve designed their dispensary to feel warm, welcoming, and just a little more refined, with premium brands like Seed & Strain Cannabis Co. elegantly displayed in a space that feels more like a boutique than a typical shop.
Their commitment to what they call the “Higher Experience” is built on three pillars: higher standard, higher knowledge, and higher calling.
That translates into not just better products, but better service driven by a team that’s passionate, well-trained, and genuinely excited to help you explore what cannabis can do for you.
Reverie 73
Reverie 73 is a full-spectrum cannabis destination built around education, comfort, and community impact. From the origin of their name (a nod to both dreamlike calm and the milestone year of cannabis decriminalization) to the vibe inside their space, everything at Reverie 73 is rooted in purpose.
Their team guides, informs, and uplifts every customer, creating a welcoming space for everyone. They’re goal is to make sure everyone, from curious first-timers to experienced consumers, feels at ease asking questions and learning about the plant.
The showroom is open, inviting, and intentionally designed to spark conversation and connection, and their staff approaches each customer with warmth, respect, and zero judgment.
Lowell Cannabis Co.
Lowell Cannabis Co. is all about keeping things local, accessible, and down-to-earth. As a community-centered dispensary, they’ve built a space full of high-quality cannabis that feels welcoming, relaxed, and like it belongs to the neighborhood. From flower and vapes to edibles and topicals, their shelves are stocked with a thoughtful mix of products that cater to a wide range of needs and experience levels.
But what really sets Lowell Cannabis Co. apart is their focus on affordability without sacrificing quality, which is a rare balance that makes them a Lowell favorite.

Explore the Best of Lowell’s Cannabis Scene
Lowell’s dispensary landscape is full of strong contenders, each offering something unique, whether it’s a focus on education, craft cultivation, community involvement, or simply creating a space that feels like home. No matter where you are in your cannabis journey, there’s a shop in this city ready to meet you with quality, care, and a true sense of purpose.
At Mayflower, we’re proud to be part of that movement. Our Lowell location offers a curated menu, a welcoming atmosphere, and a deep commitment to social equity through programs that give back to the community. Stop by and see what thoughtful cannabis retail looks like. We’d love to welcome you in!
The contents of this blog are intended for informational purposes only. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition.