Learn About Cannabis
The Human Endocannabinoid System
Learn how your body is naturally equipped to utilize the cannabis plant’s therapeutic benefits.
The Human Endocannabinoid System (ECS) is a complex biological network found in all mammals, playing a crucial role in regulating a range of bodily functions, such as memory, sleep, immune system responses, and more.
The ECS primarily consists of two main types of cannabinoid receptors, known as CB1 and CB2. These receptors are designed to interact with endocannabinoids, which are cannabinoids naturally produced by the body. They can also bind with cannabinoids from plants, leading to a variety of physiological effects throughout the body.
Cannabinoids have shown promise for various therapeutic applications, including antioxidant, neuroprotective, anti-inflammatory, analgesic (pain-relieving), anti-tumor, sleep-regulating, anti-psychotic, and anti-anxiety effects.
The most recognized cannabinoid, delta-9-tetrahydrocannabinol (THC), is known for creating the psychoactive effects, or “high,” associated with cannabis, influencing perception, mood, emotions, cognitive function, and motor skills. In contrast, there are many other cannabinoids, like cannabidiol (CBD), which do not produce a high but still offer significant medical benefits.
Cannabinoids
Cannabinoids are chemical substances produced by cannabis flowers that interact with brain receptors to alleviate various symptoms, such as pain, nausea, anxiety, and inflammation. While all cannabinoids contribute to symptom relief for certain conditions, THC and CBD are the two most well-known and widely studied cannabinoids.
When cannabis is consumed, cannabinoids attach to receptor sites throughout the brain (CB-1 receptors) and the body (CB-2 receptors). The effects of cannabinoids vary depending on which receptors they interact with. THC primarily binds to CB1 receptors in the brain’s central nervous system, leading to cerebral and behavioral effects, such as a high or feeling of euphoria. In contrast, CBD mainly targets CB2 receptors located in the peripheral nervous system and associated with the immune system. The activation of CB2 receptors can promote relaxation, aid in bodily repair, and alleviate pain without affecting cognitive function.
Terpenes
Terpenes are fragrant compounds found in various plants, contributing to their distinct aromas, such as linalool in lavender and limonene in oranges. Some terpenes also serve protective functions for the plants and can offer similar benefits when consumed by humans.
The six most prevalent terpenes in cannabis are Limonene, Humulene, Pinene, Linalool, Caryophyllene, and Myrcene. Use this guide to understand which terpenes may produce your desired effects.
Both cannabinoids and terpenes offer unique therapeutic benefits, and their properties can complement each other when consumed together.
This combined effect, known as the “Entourage Effect,” makes them more effective together than when used separately.
Cannabis Strains
Cannabis strains are historically sorted into three categories: Sativa, Indica and Hybrid. Each strain has it’s own range of effects on the body and mind, resulting in a wide range of medicinal benefits.
- Sativas are said to provide invigorating, uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects.
- Indica strains are known to be physically sedating, perfect for relaxing with a movie or as a nightcap before bed.
- Hybrids are thought to fall somewhere in between, offering a balance of indica and sativa effects.
While the strain can be a great start to determining which cannabis products are best for you, it is also important to know which cannabinoids and terpenes are present. Ultimately, the combination of all of these properties is what will form the desired effects.
View Mayflower Strains
Consumption
Choosing the right cannabis consumption method is essential for achieving the desired effects. Advances in cannabis product development have introduced several methods, including inhalation, ingestion, absorption, and topical application, each tailored for different uses and preferences. Speak with a certified pharmacist to find the most suitable method for your needs.
INHALATION: Vaporized Flower, Oils & Extracts
Inhalation methods involve breathing cannabis into the lungs, where it quickly enters the bloodstream. Vaporizers produce vapor rather than smoke, offering a clean and fast-acting way to consume cannabis.
SUBLINGUAL: Tinctures & Sprays
Tinctures and sprays are sublingual cannabis products that deliver liquid extracts under the tongue. These are popular among users who want quick effects and controlled dosing without smoking. Tinctures come with different levels of THC, allowing users to choose their preferred potency.
TOPICAL: Patches, Salves, Lotions & Oils
Topical cannabis products are designed for application directly onto the skin and are believed not to induce the mental effects often referred to as “being high.” This makes them a good option for those seeking targeted relief from conditions like muscle soreness while maintaining a clear head.
ORAL INGESTION: Capsules & Edibles
Consuming cannabis orally, through edibles or capsules, provides a different experience from other methods because the effects take longer to set in but are often more intense and last longer. These products are known for producing powerful full-body effects based on the dosage consumed.
